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"From NBC news Aug 30 2022" The updated Covid vaccine boosters, a reformulated version targeting the BA.5 omicron subvariant, could be available around Labor Day. They'll be the first Covid shots distributed without results from human trials. Does that matter?
Because the Biden administration has pushed for a fall booster campaign to begin in September, the mRNA vaccine-makers Pfizer-BioNTech and Moderna have only had time to test the reformulated shots in mice, not people. That means the Food and Drug Administration is relying on the mice trial data — plus human trial results from a similar vaccine that targets the original omicron strain, called BA.1 — to evaluate the new shots, according to a recent tweet from the FDA commissioner, Dr. Robert Califf.
That could be a potentially risky bet, experts say, if the shots don’t work as well as hoped.
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