Reply
Regular Contributor

DES Info: Are there any problems with 3rd Generation: Grandmother took DES (Diethylstilbestrol)

 
Slide17.JPGSeveral reports have examined DES grandchildren for possible abnormalities.
 
For the granddaughters, these studies indicate that the age of first menstruation is not affected by DES, but that DES-exposed granddaughters have a greater likelihood of menstrual irregularity.
 
In a small clinical study that included pelvic exams, researchers found no evidence of DES-related changes in the granddaughters of women given DES during pregnancy.
 
A study of cancer outcomes in the granddaughters and grandsons showed no overall increased risk of cancer in either gender.
 
An excess of ovarian cancer was seen in the granddaughters of exposed women, but the number of cases was small, so the evidence is considered preliminary.
 
Investigations in Holland and France have shown a higher risk of hypospadias (a genitourinary anomaly) in the grandsons of DES-exposed women, but DES exposure was not verified in these studies.
 
An analysis of NCI data suggested an increased risk of hypospadias in DES-exposed grandsons, but the finding was not conclusive.
 
A study conducted in Holland found an increased risk of tracheo-esophageal fistula in granddaughters, but this also was not seen in the NCI data.
 
DES Follow-up Study
National Cancer Institute
#Diethylstilbestrol
#TheDESTragedy
DESInfo411@gmail.com
KMFDallas
0 Kudos
1,719 Views
0
Report
cancel
Showing results for 
Show  only  | Search instead for 
Did you mean: 
Users
Announcements

Ask the Expert: Social Security

Discuss your thoughts about the 2022 Social Security cost-of-living adjustment with AARP experts - and ask a question to earn 50 AARP Rewards points. Join the discussion now.


AARP Make Your Move Contest 2021

Enter Today! Ends 10/22/2021. See Official Rules

Test Your Knowledge, Score Big. New Game Each Day!

AARP's new Right Again! Trivia game - part trivia, part puzzle, all fun! Special opportunities for AARP Members and Rewards participants. Play Now.

AARP Right Again! Trivia

AARP Rewards

Activate AARP Rewards to earn points for games, quizzes and videos. Redeem for deals and discounts. Get started with AARP Rewards now!

AARP Rewards Badge

Music and Brain Health

From soft jazz to hard rock - discover music's mental, social and physical benefits. Learn more.

Music and Brain Health